Recombinant Ñ-peptide (human)
Cat. Number | BioAL-000004 |
Description | Insulin
is a peptide hormone produced in beta-cells of the Langerhans islets. The
main effect of insulin is the decrease of glucose concentration in plasma.
Insulin increases the penetrability of plasmatic membranes for glucose,
activates key glycolysis enzymes, stimulates glycogen formation in liver and
muscles, enhances lipid and protein biosynthesis. Insulin also inhibits
activity of lipolytic and glycogenolytic enzymes. Insufficient insulin secretion as a result of beta-cells destruction - an absolute insulin deficiency - is a key element of type I diabetes pathogenesis. Decreased tissue sensitivity to insulin - a relative insulin deficiency - plays an important role in the development of type I diabetes. |
Name | Recombinant Ñ-peptide (human) |
Synonym | insulin |
Amino acid sequence | EAEDLQVGQV ELGGGPGAGS LQPLALEGSL Q |
Molecular weight | 3020,30 Da |
Natural Source | Homo sapiens |
Expression system | E. coli |
Physical Appearance | Lyophilized substance, white powder |
Storage conditions | Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. |
Purity | >98% HPLC was carried out on Prosphere column (C18 300A 5u, Alltech) in 0.1% TFA with 10 – 80% acetonitrile gradient at flow rate 0.75 mL/min |
Usage | For Research only |
Availability | Email: sale@alinda.ru |
Price Category | |
Prices, USD | |
Supplier | Alinda Chemical Ltd. |