Recombinant Ñ-peptide (human)

Cat. Number BioAL-000004
Description Insulin is a peptide hormone produced in beta-cells of the Langerhans islets. The main effect of insulin is the decrease of glucose concentration in plasma. Insulin increases the penetrability of plasmatic membranes for glucose, activates key glycolysis enzymes, stimulates glycogen formation in liver and muscles, enhances lipid and protein biosynthesis. Insulin also inhibits activity of lipolytic and glycogenolytic enzymes.

Insufficient insulin secretion as a result of beta-cells destruction - an absolute insulin deficiency - is a key element of type I diabetes pathogenesis. Decreased tissue sensitivity to insulin - a relative insulin deficiency - plays an important role in the development of type I diabetes.
Name Recombinant Ñ-peptide (human)
Synonym insulin
Amino acid sequence EAEDLQVGQV ELGGGPGAGS LQPLALEGSL Q
Molecular weight 3020,30 Da
Natural Source Homo sapiens
Expression system E. coli
Physical Appearance Lyophilized substance, white powder
Storage conditions Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Purity >98%
HPLC was carried out on Prosphere column (C18 300A 5u, Alltech) in 0.1% TFA with 10 – 80% acetonitrile gradient at flow rate 0.75 mL/min
Usage For Research only
Availability Email: sale@alinda.ru
Price Category
Prices, USD
Supplier Alinda Chemical Ltd.