Exendin-4
Cat. Number | BioAL-000020 |
Description | Recombinant
exendin-4 is a glucagon-like peptide-1 originally isolated from intestines of
Heloderma suspectum. It shows 50% sequence similarity to mammalian
glucagon-like peptide-1 (GLP-1). It stimulates insulin secretion without
drastic decrease of plasma glucose concentration that usually takes place as
a result of the use of insulin and other antidiabetic drugs. The latest
investigations have resulted in the creation of a unique drug for type 2
diabetes on the basis of the saliva of Heloderma suspectum. Exendin-4 enhances glucose-dependent insulin secretion, but supresses glucagon secretion. It also stimulates B-cell proliferation. |
Name | Exendin-4 |
Synonym | CAS: 141758-74-9 |
Amino acid sequence | HGEGTFTSDL SKQMEEEAVR LFIEWLKNGG PSSGAPPPS |
Molecular weight | 4186,57 Da |
Natural Source | E. coli |
Expression system | E. coli |
Physical Appearance | Colourless clear liquid |
Storage conditions | Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. |
Purity | >
80 % PAGE analysis of the recombinant Exendin-4 E.coli |
Usage | For Research only |
Availability | Email: sale@alinda.ru |
Price Category | |
Prices, USD | |
Supplier | Alinda Chemical Ltd. |