Exendin-4
| Cat. Number | BioAL-000020 |
| Description | Recombinant
exendin-4 is a glucagon-like peptide-1 originally isolated from intestines of
Heloderma suspectum. It shows 50% sequence similarity to mammalian
glucagon-like peptide-1 (GLP-1). It stimulates insulin secretion without
drastic decrease of plasma glucose concentration that usually takes place as
a result of the use of insulin and other antidiabetic drugs. The latest
investigations have resulted in the creation of a unique drug for type 2
diabetes on the basis of the saliva of Heloderma suspectum. Exendin-4 enhances glucose-dependent insulin secretion, but supresses glucagon secretion. It also stimulates B-cell proliferation. |
| Name | Exendin-4 |
| Synonym | CAS: 141758-74-9 |
| Amino acid sequence | HGEGTFTSDL SKQMEEEAVR LFIEWLKNGG PSSGAPPPS |
| Molecular weight | 4186,57 Da |
| Natural Source | E. coli |
| Expression system | E. coli |
| Physical Appearance | Colourless clear liquid |
| Storage conditions | Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. |
| Purity | >
80 % PAGE analysis of the recombinant Exendin-4 E.coli |
| Usage | For Research only |
| Availability | Email: sale@alinda.ru |
| Price Category | |
| Prices, USD | |
| Supplier | Alinda Chemical Ltd. |