Exendin-4

Cat. Number BioAL-000020
Description Recombinant exendin-4 is a glucagon-like peptide-1 originally isolated from intestines of Heloderma suspectum. It shows 50% sequence similarity to mammalian glucagon-like peptide-1 (GLP-1). It stimulates insulin secretion without drastic decrease of plasma glucose concentration that usually takes place as a result of the use of insulin and other antidiabetic drugs. The latest investigations have resulted in the creation of a unique drug for type 2 diabetes on the basis of the saliva of Heloderma suspectum.

Exendin-4 enhances glucose-dependent insulin secretion, but supresses glucagon secretion. It also stimulates B-cell proliferation.
Name Exendin-4
Synonym  CAS: 141758-74-9
Amino acid sequence HGEGTFTSDL SKQMEEEAVR LFIEWLKNGG PSSGAPPPS
Molecular weight 4186,57 Da
Natural Source E. coli
Expression system E. coli
Physical Appearance Colourless clear liquid
Storage conditions Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Purity > 80 %
PAGE analysis of the recombinant Exendin-4 E.coli
Usage For Research only
Availability Email: sale@alinda.ru
Price Category
Prices, USD
Supplier Alinda Chemical Ltd.